Center for Immunotherapy and Cell-Based Technologies
Novosibirsk — Kaliningrad — Moscow — IrkutskTrifunctional Antibody Catumaxomab Triggers Vaccination Effect Against Cancer
TRION Pharma GmbH announces today that the results from two different studies demonstrate catumaxomab's capacity to activate the immune system in a way that can otherwise only be achieved through vaccination. The data were obtained by two independent research teams using catumaxomab in malignant ascites and gastric cancer, respectively...
Immunotherapy for cancer
An active specific immunotherapy (vaccinotherapy) is a strategy using tumor-associated antigens for including antitumor immune responses. The small structural distinctions of the xenogenic tumor-associated antigens from their human analogues render these antigens highly immunogenic and capable of including immune-mediated, antitumor responses in a patient not only at early, but also at advanced stages of disease, when tumor-derived immunosuppression is significant. Tumor-specfic immunotherapy is able to generate a selective and long-term antitumor effect. Such a therapy has no complications attributable to chemotherapy.
