Center for Immunotherapy and Cell-Based Technologies
Novosibirsk — Kaliningrad — Moscow — IrkutskPhase III Trial Of Novartis Drug Afinitor® Met Primary Endpoint Of Reducing SEGA Tumor Size In Patients With Tuberous Sclerosis
Novartis Pharmaceuticals Corporation ("Novartis") announced Phase III trial results that showed more than one-third of patients taking Afinitor® (everolimus) tablets experienced a 50% or greater reduction in the size of their subependymal giant cell astrocytomas (SEGAs), non-cancerous brain tumors associated with tuberous sclerosis complex (TSC)(1,2,6)...
Immunotherapy for cancer
An active specific immunotherapy (vaccinotherapy) is a strategy using tumor-associated antigens for including antitumor immune responses. The small structural distinctions of the xenogenic tumor-associated antigens from their human analogues render these antigens highly immunogenic and capable of including immune-mediated, antitumor responses in a patient not only at early, but also at advanced stages of disease, when tumor-derived immunosuppression is significant. Tumor-specfic immunotherapy is able to generate a selective and long-term antitumor effect. Such a therapy has no complications attributable to chemotherapy.
